Cortactin(Phospho Tyr466) Polyclonal Antibody, 50ul Yeast Expression An important paralog of this

An important paralog of this gene is COL8A1

Interacts with 14-3-3 family members in a phosphorylation-dependent manner

elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor

Mutations in this gene are associated with lung cancer

Cortactin(Phospho Tyr466) Polyclonal Antibody, 50ul Yeast Expression An important paralog of thisThis gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase