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SETB2 Polyclonal Antibody, 100ul Mini dry bath Stimulates cancer-associated fibroblast (CAF) proliferation

SKU: 10989492212

4.2
USD123.75 USD147.75

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SETB2 Polyclonal Antibody, 100ul Mini dry bath Stimulates cancer-associated fibroblast (CAF) proliferationThis gene encodes a member of a family of proteins that contain a methyl CpG binding domain (MBD) and a SET domain and function as histone methyltransferases. This protein is recruited to heterochromatin and plays a role in the regulation of chromosome segregation. This region is commonly deleted in chronic lymphocytic leukemia. Naturally occuring readthrough transcription occurs from this gene to the downstream PHF11 (PHD finger protein 11) gene.

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Description

Stimulates cancer-associated fibroblast (CAF) proliferation by a rapid genomic response through the EGFR/ERK transduction pathway

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proliferation and survival in the adult and the embryo

This protein may have a role in efficient chromosome congression and segregation by promoting microtubule-dependent microtubule amplification

SETB2 Polyclonal Antibody, 100ul Mini dry bath Stimulates cancer-associated fibroblast (CAF) proliferationThis gene encodes a member of a family of proteins that contain a methyl CpG binding domain (MBD) and a SET domain and function as histone methyltransferases. This protein is recruited to heterochromatin and plays a role in the regulation of chromosome segregation. This region is commonly deleted in chronic lymphocytic leukemia. Naturally occuring readthrough transcription occurs from this gene to the downstream PHF11 (PHD finger protein 11) gene.

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