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IRS-1 Polyclonal Antibody, 50ul[BT-AP04650] Gene Synthesis While the primary structure of

SKU: 10016684727

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PLN162.00 PLN195.00

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IRS-1 Polyclonal Antibody, 50ul[BT-AP04650] Gene Synthesis While the primary structure ofIRS1 encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.

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Description

While the primary structure of transglutaminases is not conserved

Inflammatory stimuli can induce IKK-mediated phosphorylation of PIAS1 at Ser90

This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway

A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B

IRS-1 Polyclonal Antibody, 50ul[BT-AP04650] Gene Synthesis While the primary structure ofIRS1 encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.

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